Synthesis of optically-active benzylic amines; asymmetric reduction of ketoxime ethers with chiral oxazaborolidines

Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications

E. J. Corey, Raman K. Bakshi, Saizo Shibata · Journal of the American Chemical Society · 1987 · 1.4K citations

Natural Sciences, Chemistry, Biocatalysis +10

Asymmetric syntheses with chiral oxazaborolidines

Sabine Wallbaum, Jürgen Martens · Tetrahedron Asymmetry · 1992 · 382 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Asymmetric reduction of aromatic ketones with chiral alkoxy-amineborane complexes

Akira Hirao, Shinichi Itsuno, Seiichi Nakahama et al. · Journal of the Chemical Society Chemical Communications · 1981 · 217 citations

Natural Sciences, Chemistry, Organic Chemistry +4

Asymmetric synthesis using chirally modified borohydrides. Part 3. Enantioselective reduction of ketones and oxime ethers with reagents prepared from borane and chiral amino alcohols

Shinichi Itsuno, Michio Nakano, Koji Miyazaki et al. · Journal of the Chemical Society Perkin Transactions 1 · 1985 · 190 citations

Natural Sciences, Chemistry, Biocatalysis +9

Catalytic Behavior of Optically Active Amino Alcohol–Borane Complex in the Enantioselective Reduction of Acetophenone Oxime <i>O</i>-Alkyl Ethers

Shinichi Itsuno, Yoshiki Sakurai, Koichi Ito et al. · Bulletin of the Chemical Society of Japan · 1987 · 167 citations

Natural Sciences, Chemistry, Catalysis +6