Influence of cross-linked hyaluronic acid hydrogels on neurite outgrowth and recovery from spinal cord injury

Abstract

The use of a cross-linked HA scaffold promoted robust neurite outgrowth. Although there was no benefit from the polymer in a rodent spinal cord injury model, the findings in this study represent an early step in the development of semisynthetic extracellular matrice scaffolds for the treatment of neuronal injury.