Epithelial basement membrane thickening is related to <scp>TGF</scp>‐Beta 1 expression in children with chronic respiratory diseases

Abstract

Increased BM thickness and number of TGF-β1 positive epithelial cells were found in children with asthma, CF and PCD. The number of TGF-β1 positive cells correlated positively with the BM thickness in all groups. We suggest that this might be a common generic feature of bronchial remodelling in chronic respiratory diseases.