Biotechnology & Biotechnological Equipment · 2014 · 48 citations · 4 references
MedicineDermatologyPharmacotherapyBiophotonicsPain ManagementPain MedicineBiomedical Laser ApplicationsLaser SurgeryLaser-tissue InteractionPhotothermal TherapyAblative Laser TherapyAphthous Ulcer ManagementClinical Pain AssessmentPain Intensity MonitoringPain Intensity Rating ScalesPower OutputSkin ErythemaTreatment Parameters
once daily); group 2 (controls) - 90 patients who received pharmacotherapy (Granofurin and solcoseryl given twice daily). The indices we assessed were pain intensity, erythema dynamics and epithelization time. Pain was completely managed in 55.6% of group 1 patients one day after therapy began, while it took three days to alleviate pain for 11.1% of the patients in group 2. The erythema was managed entirely in 24.4% of group 1 patients after the first session, while it did not change in any of the group 2 patients. Pain intensity and erythema had similar dynamics for both groups. In 5 days, 75.6% of group 1 patients showed complete epithelization, while in group 2 the process was completed in only 37.8% of patients. As a whole, the results we obtained using LLLT to treat chronic RAS were better than those obtained in the group receiving pharmacotherapy. Pain and inflammation were very effectively managed with LLLT with the parameters we used and epithelization was considerably accelerated.
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