COCCIDIOIDAL GRANULOMA

Abstract

Cases of coccidioidal granuloma are of increasing interest to those of us living in California. The disease was first described by Posadas¹in Buenos Aires in 1900, the same case having been observed and reported independently by Wernicke²in 1892. Rixford,³in 1894, recognized the first case in California. This case with another observed by Thorne⁴was described later in greater detail by Rixford and Gilchrist,⁵who believed that the infecting organism was a protozoan belonging to the group of<i>Coccidia</i>, and suggested the name of<i>Coccidioides immitis</i>for the organism. Ophüls and Moffit,⁶in 1900, observed another case and found that the parasite grew readily on artificial mediums and developed a mold. It apparently belonged to the group of<i>Oidia</i>. Ophüls⁷then gave the name of<i>Oidium coccidioides</i>to the parasitic organism and coccidioidal granuloma to the lesion produced by it. It