Cellular Association and Cargo Release of Redox‐Responsive Polymer Capsules Mediated by Exofacial Thiols

Yan Yan, Yajun Wang, Joan K. Heath, Edouard C. Nice, Frank Caruso

Advanced Materials · 2011 · 106 citations · 22 references

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Abstract

Redox-responsive polymer capsules stabilized by disulfide bonds and loaded with hydrophobic cargo are prepared by templating mesoporous silica particles via layer-by-layer assembly. The thiols and disulfide bonds in the capsules interact with the exofacial thiols on the cell membrane, which regulate cellular association and cargo release from the capsules. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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