Short‐Term Fasting Differentially Alters PACAP and VIP Levels in the Brains of Rat and Chicken

R. Józsa, József Németh, Andrea Tamás, Tibor Hollósy, Andrea Lubics, Balázs Jakab, A. Oláh, Istvàn Lengvári, Akira Arimura, Dóra Reglődi

Annals of the New York Academy of Sciences · 2006 · 21 citations · 15 references

DOIFull text

Open access

Concepts

Abstract

The present article investigated the levels of pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) in the brains of rats and chickens 12, 36, and 84 h after starvation. PACAP levels increased in both species, 12 h after food deprivation in rats, and with a 24-h delay in chickens. VIP levels showed a more complex pattern: a gradual increase in the hypothalamus and telencephalon, and a significant decrease in the brain stem of rats. In chickens, a decrease was observed in every brain area after 36 h of starvation. These data show that PACAP and VIP are differentially regulated and are involved in the regulatory processes under a food-restricted regimen, and are differentially altered in nocturnal and diurnal species.

References

15