Treatment of medullary thyroid carcinoma by combined expression of suicide and interleukin-2 genes

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

Kenneth W. Culver, Zvi Ram, Stuart Wallbridge et al. · Science · 1992 · 1.5K citations

Medicine, Cancer Biology, Oncology +17

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

Sara M. Freeman, Camille N. Abboud, Katharine A. Whartenby et al. · PubMed · 1993 · 1.1K citations

Medicine, Cancer Biology, Oncology +10

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy.

Frederick L. Moolten · PubMed · 1986 · 972 citations

Medicine, Genetics, Oncology +16

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

Eric R. Fearon, Drew M. Pardoll, Toshiuki Itaya et al. · Cell · 1990 · 922 citations

Life Sciences, Immunology, Oncology +17

Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques.

Ralf Gold, M. Schmied, Gerhard Giegerich et al. · PubMed · 1994 · 685 citations

Veterinary Medicine, Cell Biology, Pathology +8