Internal Medicine · 2009 · 12 citations · 6 references
MedicineClinical SciencesInternal MedicineGastroenterologyPediatric EndocrinologyPediatric GastroenterologyColonic DiseasesColonic DisordersGastric DiseasesGastric DisordersGastrointestinal DiseaseGastrointestinal PathologyAlbumin QuantificationColonic PolypsGastric PathologyGastrointestinal PolypsJuvenile Polyposis SyndromePediatric Gastrointestinal PathologyProtein Digestion Disorders
A male patient with chronic bloody stool was diagnosed as juvenile polyposis at the age of 28. He had thirty to forty colonic polyps and some were removed endoscopically, while gastric polyps were too numerous to intervene. As the polyposis advanced gradually, the patient developed intractable anemia and serious hypoproteinemia. Albumin scintigram revealed protein losing gastropathy due to progressive gastric polyposis. Total gastrectomy was carried out at the age of 34 and the patient has achieved remarkable and sustainable improvement.
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Mutations in the <i>SMAD4/DPC4</i> Gene in Juvenile Polyposis
James R. Howe, Stina Roth, John C. Ringold et al. · Science · 1998 · 897 citations
Familial juvenile Polyposis of the Stomach
Akiharu Watanabe, Hideo Nagashima, Makoto Motoi et al. · Gastroenterology · 1979 · 94 citations
Medicine, Pathobiology, Pathology +10