Increased risk for endocrine autoimmunity in Italian type 2 diabetic patients with GAD65 autoantibodies

Abstract

Our study demonstrates that the presence of GAD65Ab identifies a subgroup of type 2 diabetic patients with high risk for thyroid and adrenal autoimmunity, and that both GAD65Ab and TPOAb are associated with the presence of HLA-DR3-DQ2, in these patients.