Concepedia

Brain uptake of ketoprofen–lysine prodrug in rats

Mikko Gynther, Aaro J. Jalkanen, Marko Lehtonen, Markus Forsberg, Krista Laine, Jarmo Ropponen, Jukka Leppänen, Jarkko Rautio

International Journal of Pharmaceutics · 2010 · 77 citations · 20 references

DOI

Concepts

References

20

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

Peter Ertl, Bernhard Rohde, Paul M. Selzer · Journal of Medicinal Chemistry · 2000 · 3K citations

, , +15

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

Peter Teismann, Kim Tieu, Dong‐Kug Choi et al. · Proceedings of the National Academy of Sciences · 2003 · 659 citations · Full text

, , +17

Selective expression of the large neutral amino acid transporter at the blood–brain barrier

Rubén J. Boado, Jian Yi Li, Marie Nagaya et al. · Proceedings of the National Academy of Sciences · 1999 · 479 citations

, , +12

Influence of nonspecific brain and plasma binding on CNS exposure: implications for rational drug discovery

J. Cory Kalvass, Tristan S. Maurer · Biopharmaceutics & Drug Disposition · 2002 · 415 citations

, , +15

Transport of Amino Acid-Related Compounds Mediated by L-Type Amino Acid Transporter 1 (LAT1): Insights Into the Mechanisms of Substrate Recognition

Hiroshi Uchino, Yoshikatsu Kanai, Do Kyung Kim et al. · Molecular Pharmacology · 2002 · 406 citations

, , +11