Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis - Concepedia

Concepedia

Publication | Closed Access

Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

180

Citations

44

References

2007

Year

Jocea M. R. van Amelsfort, Joël A. G. van Roon, Madelon Noordegraaf, Kim M. G. Jacobs, J. W. J. Bijlsma, Floris P. J. G. Lafeber, Leonie S. Taams

Arthritis & Rheumatism

Abstract

Our findings suggest that the interaction of CD4+,CD25+ Treg cells with activated monocytes in the joint might lead to diminished suppressive activity of CD4+,CD25+ Treg cells in vivo, thus contributing to the chronic inflammation in RA.

References

	Year	Citations

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