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Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin

Signal TransductionSignaling PathwayCell RegulationMedicineReceptor Tyrosine KinaseAstrocytic OriginPromotes RadioresistanceCell BiologyCell GrowthRadiation OncologyPhosphatidylinositol-3 Kinase/akt PathwayGliomaCell SignalingTumor Biology