Concepedia

TOTAL SYNTHESIS OF METHYNOLIDE: SYNTHESIS OF TWO INTERMEDIATES, 3,4-DIACETOXY-3-METHYL-1-HEXYNE AND PRELOG-DJERASSI LACTONIC ACID

Akio Nakano, Seiji Takimoto, Junji Inanaga, Tsutomu Katsuki, Shuichi Ouchida, Kazutaka Inoue, Makoto Aiga, Nobuhisa Okukado, Masaru Yamaguchi

Chemistry Letters · 1979 · 23 citations · 7 references

DOI

Concepts

Abstract

Abstract (+)-3,4-Diacetoxy-3-methyl-1-hexyne and (+)-Prelog-Djerassi lactonic acid were synthesized as the starting materials for the total synthesis of methynolide.

References

7

Erythromycin. X.<sup>1</sup> Structure of Erythromycin

Paul F. Wiley, Koert Gerzon, Edwin H. Flynn et al. · Journal of the American Chemical Society · 1957 · 154 citations

, , +6

Syntheses of macrolide antibiotics. I. Methymycin

Satoru Masamune, C. U. Kim, Kenneth E. Wilson et al. · Journal of the American Chemical Society · 1975 · 137 citations

, , +8

The Structure of the Antibiotic Methymycin<sup>1</sup>

Carl Djerassi, John A. Zderic · Journal of the American Chemical Society · 1956 · 90 citations

, , +5

New Antibacterial Agents. 2-Acylamino-1-(4-hydrocarbonylsulfonylphenyl)-1,3-propanediols and Related Compounds

Royal A. Cutler, Richard J. Stenger, C. M. Suter · Journal of the American Chemical Society · 1952 · 75 citations

, , +8

THE STRUCTURE OF THE ANTIBIOTIC METHYMYCIN

Carl Djerassi, John A. Zderic · Journal of the American Chemical Society · 1956 · 59 citations

, , +5