Publication | Closed Access
The effect of a single-dose parenteral antibiotic in the prevention of wound infection a controlled trial
21
Citations
7
References
1972
Year
SurgeryDrug ResistanceAntimicrobial StewardshipHealthcare-associated InfectionSepsisAntimicrobial TherapyInfection ControlAnti-infective AgentsAntimicrobial ResistanceSingle-dose Parenteral AntibioticSignificant ReductionSingle DoseWound InfectionAntimicrobial PharmacokineticsWound-infection RateAntibioticsWound HealingAntimicrobial PharmacodynamicsMedicineAnesthesiology
Abstract In a series of 349 operations a single dose of 500 mg. of ampicillin was given immediately preoperatively to 164 patients selected at random. There was no significant reduction in the wound-infection rate in cases given ampicillin compared with the controls.
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