Gastroprotective activity of atractylenolide III from <i>Atractylodes ovata</i> on ethanol-induced gastric ulcer <i>in vitro</i> and <i>in vivo</i>

Abstract

Atractylenolide III was the major gastroprotective component of A. ovata in ethanol-induced acute gastric ulcer. It is suggested that the gastroprotective mechanism of atractylenolide III was via inhibition of the MMP-2 and MMP-9 pathway.