Inertial migration of deformable capsules in channel flow

Abstract

Using three-dimensional computer simulations, we study the cross-stream inertial migration of neutrally buoyant deformable particles in a pressure-driven channel flow. The particles are modeled as elastic shells filled with a viscous fluid. We show that the particles equilibrate in a channel flow at off-center positions that depend on particle size, shell compliance, and the viscosity of encapsulated fluid. These equilibrium positions, however, are practically independent of the magnitude of channel Reynolds number in the range between 1 and 100. The results of our studies can be useful for sorting, focusing, and separation of micrometer-sized synthetic particles and biological cells.