TGF-beta inhibits human cutaneous melanoma cell migration and invasion through regulation of the plasminogen activator system

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.6K citations · Full text

Somatic Variant, Braf Gene, Genetics +5

The serpin PAI-1 inhibits cell migration by blocking integrin αvβ3 binding to vitronectin

Steingrimur Stefansson, Daniel A. Lawrence · Nature · 1996 · 676 citations

Signal Transduction, Integrin αVβ3, Cell Signaling +11

Activation of Matrix Metalloproteinase-9 (MMP-9) via a Converging Plasmin/Stromelysin-1 Cascade Enhances Tumor Cell Invasion

NOEMI RAMOS‐DeSIMONE, Elizabeth Hahn-Dantona, John Sipley et al. · Journal of Biological Chemistry · 1999 · 592 citations · Full text

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford et al. · Pigment Cell Research · 2006 · 561 citations

Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants

Roberta Mazzieri, Laura Masiero, Lucia Zanetta et al. · The EMBO Journal · 1997 · 419 citations · Full text

Signal Transduction, Regulatory Mechanism, Urokinase-plasmin System +9