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In vitro-induced resistance to the deoxycytidine analogues cytarabine (AraC) and 5-aza-2′-deoxycytidine (DAC) in a rat model for acute myeloid leukemia is mediated by mutations in the deoxycytidine kinase (dck) gene

Hematological MalignancyMolecular PharmacologyVitro-induced ResistanceAcute Myeloid LeukemiaMedicineMyeloid NeoplasiaCancer Cell BiologyPharmacotherapyAnti-cancer AgentPharmacologyCell BiologyRat ModelTumor BiologyDrug Resistance