Heterogeneity of HPA‐3 alloantibodies: consequences for the diagnosis of alloimmune thrombocytopenic syndromes

Abstract

Anti-HPA-3 alloantibodies show considerable heterogeneity, which may hamper the serologic diagnosis of FNAIT. Preservation of the alphaIIbbeta3 integrin and protection from enzymatic degradation seem to be important during PLT storage.