Concepedia

A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours

Antoine Hollebecque, Nadine Houédé, Ezra E.W. Cohen, Christophe Massard, Antoine Italiano, Paul Westwood, William Bumgardner, J. A. Miller, Les Brail, Karim A. Benhadji,

European Journal of Cancer · 2014 · 34 citations · 16 references

DOI

Concepts

References

16

Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin

Gregory J. Brunn, Christine C. Hudson, Aleksandar Sekulić et al. · Science · 1997 · 960 citations

, , +17

TOR controls translation initiation and early G1 progression in yeast.

Nik Barbet, Ulrich Schneider, Stephen B. Helliwell et al. · Molecular Biology of the Cell · 1996 · 735 citations · Full text

, , +17

S6K1- and ßTRCP-Mediated Degradation of PDCD4 Promotes Protein Translation and Cell Growth

N. Valerio Dorrello, Angelo Peschiaroli, Daniele Guardavaccaro et al. · Science · 2006 · 712 citations

, , +17

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

Brian Raught, Franck Peiretti, Anne‐Claude Gingras et al. · The EMBO Journal · 2004 · 461 citations · Full text

, , +14

Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma1

Michael D. Prados, Kathleen R. Lamborn, Susan M. Chang et al. · Neuro-Oncology · 2006 · 219 citations · Full text

, , +17