New Mechanistic Insights Regarding Pd/Cu Catalysts for the Sonogashira Reaction: HRMAS NMR Studies of Silica-Immobilized Systems

Abstract

The title technique, high-resolution magic angle spinning NMR of suspensions, constitutes a powerful new tool for investigating the structures and mobilities of immobilized species and, thus, for optimizing heterobimetallic catalyst systems, such as the Sonogashira coupling of terminal alkynes and aryl halides.