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Cytotoxic Triterpenoids from the Rhizomes of <i>Astilbe chinensis</i>
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2009
Year
BiologyCytotoxic EffectsMedicinal ChemistryBiochemistryMedicineNatural SciencesCytotoxic TriterpenoidsAstilbe ChinensisNew TriterpenoidsPhytopharmacologyToxicologyPhytochemicalPhytochemistryPharmacologyDrug Discovery
Six new triterpenoids (1-6) with a carboxylic acid functionality at C-27 were isolated from the rhizomes of a Korean native perennial herb, Astilbe chinensis, along with nine known triterpenoids. The structures of 1-6 were elucidated on the basis of spectroscopic data interpretation. All compounds isolated were evaluated for cytotoxic effects against a small panel of human cancer lines.
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