Angewandte Chemie International Edition · 2013 · 315 citations · 56 references
Natural SciencesChemistryCatalysisInorganic ChemistryOrganic ChemistryChemical ReactionsMetal-ligand BondingArylation ReactionsTransition-metal-catalyzed Functionalization
Metal-free: The first metal-free aryltrifluoromethylation of activated alkenes has been developed. With this method, trifluoromethylated isoquinolinediones, spirobicycles, oxindoles, and α-aryl-β-trifluoromethylamides were obtained with high control of the regioselectivity. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
56
The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides
Eun Jin Cho, Todd D. Senecal, Tom Kinzel et al. · Science · 2010 · 779 citations