Publication | Closed Access
Synthesis of (<i>Z</i>)-Ligustilide
12
Citations
7
References
1993
Year
2-Formylbenzoic AcidFirst SynthesisEngineeringOrganic ChemistryBirch ReductionChemistryNatural Product SynthesisSynthetic ChemistryInorganic SynthesisBiomolecular Engineering
Abstract The first synthesis of ligustilide (1) is described, starting from 2-formylbenzoic acid (2). The key step in synthesis is the Birch reduction of 3-hydroxybutyl-phthalide (4).
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