Promoter Hypermethylation of the Bone Morphogenetic Protein-6 Gene in Malignant Lymphoma

Abstract

BMP-6 promoter was hypermethylated more often in aggressive types of lymphomas, and the hypermethylation is likely to be related to the histologic type of lymphomas. BMP-6 promoter methylation may be a potential new biomarker of risk prediction in DLBCL.