Model Studies Indicate That Copper Phenanthroline Induces Direct Strand Breaks via β-Elimination of the 2‘-Deoxyribonolactone Intermediate Observed in Enediyne Mediated DNA Damage

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTModel Studies Indicate That Copper Phenanthroline Induces Direct Strand Breaks via β-Elimination of the 2'-Deoxyribonolactone Intermediate Observed in Enediyne Mediated DNA DamageTongqian Chen and Marc M. GreenbergView Author Information Department of Chemistry, Colorado State University Fort Collins, Colorado 80523 Cite this: J. Am. Chem. Soc. 1998, 120, 15, 3815–3816Publication Date (Web):April 4, 1998Publication History Received2 January 1998Published online4 April 1998Published inissue 1 April 1998https://pubs.acs.org/doi/10.1021/ja9800075https://doi.org/10.1021/ja9800075rapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views272Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Genetics,Kinetic parameters,Oxidation,Phenyls,Reactivity Get e-Alerts