Down-regulation of β-adrenoceptors and loss of Gsα subunit levels in ventricular myocardium of rats treated with isoproterenol

G proteins and dual control of adenylate cyclase

Alfred G. Gilman · Cell · 1984 · 1.8K citations

Life Sciences, Biochemistry, Molecular Biology +12

Turning off the signal: desensitization of β‐adrenergic receptor function

William P. Hausdorff, Marc G. Caron, Robert J. Lefkowitz · The FASEB Journal · 1990 · 1.3K citations

Life Sciences, Biochemistry, Pharmacology +17

Mathematical theory of complex ligand-binding systems at equilibrium: Some methods for parameter fitting

Henry A. Feldman · Analytical Biochemistry · 1972 · 618 citations

Natural Sciences, Chemistry, Complex Systems +15

Significance of myocardial alpha- and beta-adrenoceptors in catecholamine-induced cardiac hypertrophy.

Wolfgang Zierhut, Heinz‐Gerd Zimmer · Circulation Research · 1989 · 181 citations · Full text

Medicine, Pharmacology, Physiology +17

Isoproterenol-Induced Cardiac Hypertrophy: Modifications in Characteristics of β-Adrenergic Receptor, Adenylate Cyclase, and Ventricular Contraction*

James Tse, J.R. Powell, CLAUDIA A. BASTE et al. · Endocrinology · 1979 · 120 citations

Medicine, Pharmacology, Physiology +15