BMJ · 1952 · 41 citations · 1 references
MedicineEndocrinologyPsychiatryPsychiatric PharmacotherapyPsychopharmacologySteroid BiochemistryAdrenal DisordersMental IllnessSchizophrenia PharmacotherapySchizophrenia Spectrum DisordersSteroid Metabolism DisordersSteroid PharmacologyDehydroepiandrosterone Physiology
Having noted the work of Hemphill, Reiss, and others on the relationship of "steroid" excretion to mental states, we decided to investigate the effect of dehydroisoandrosterone in selected cases of schizophrenia and ". schizoid psychopathy." Our case-material was limited to patients who showed abnormal 17-ketosteroid excretion, to patients whose mental illness was mild or who were slowly deteriorating, and, as things turned out, to patients who gave the appearance of physical immaturity.
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Stress and the General Adaptation Syndrome
Hans Selye · BMJ · 1950 · 1.4K citations · Full text