Clearance of albumin following ultrasound-induced blood–brain barrier opening is mediated by glial but not neuronal cells

Noninvasive MR Imaging–guided Focal Opening of the Blood-Brain Barrier in Rabbits

Kullervo Hynynen, Nathan McDannold, Natalia Vykhodtseva et al. · Radiology · 2001 · 1.5K citations

Medicine, Biomedical Engineering, Radiology +17

Local and reversible blood–brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications

Kullervo Hynynen, Nathan McDannold, Nickolai Sheikov et al. · NeuroImage · 2004 · 686 citations

Engineering, Biomedical Engineering, Neuroscience +12

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood–brain barrier disruption

Manabu Kinoshita, Nathan McDannold, Ferenc A. Jólesz et al. · Proceedings of the National Academy of Sciences · 2006 · 649 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex.

Walter E. Kaufmann, Paul F. Worley, Jodi A. Pegg et al. · Proceedings of the National Academy of Sciences · 1996 · 591 citations

Life Sciences, Neurobiology, Neuroscience +15

Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI‐guided focused ultrasound

Lisa H. Treat, Nathan McDannold, Natalia Vykhodtseva et al. · International Journal of Cancer · 2007 · 548 citations

Pharmacy, Pharmaceutics, Pharmacology +17