Concepedia

Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin

Jing Zhou, Choon Nam Ong, Gang Min Hur, Han‐Ming Shen

Biochemical Pharmacology · 2009 · 133 citations · 37 references

DOI

Concepts

References

37

Stat3 as an Oncogene

Jacqueline Bromberg, Melissa H Wrzeszczynska, Geeta Devgan et al. · Cell · 1999 · 2.8K citations · Full text

, , +8

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

Zhong Zhong, Zilong Wen, James Darnell · Science · 1994 · 2.1K citations

, , +14

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.7K citations · Full text

, , +16

Enhanced DNA-Binding Activity of a Stat3-Related Protein in Cells Transformed by the Src Oncoprotein

Chao‐Lan Yu, Debra J. Meyer, George S. Campbell et al. · Science · 1995 · 943 citations

, , +16

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

Sizhi Paul Gao, Kevin G. Mark, Kenneth Leslie et al. · Journal of Clinical Investigation · 2007 · 664 citations · Full text

, , +17