Cytokine mRNA expression in patients with multiple sclerosis and fatigue

Peter Flachenecker, Irene Bihler, Frank Weber, M. Gottschalk, Klaus V. Toyka, Peter Rieckmann

Multiple Sclerosis Journal · 2004 · 167 citations · 24 references

Abstract

These results suggest that TNF-alpha, as a principal proinflammatory mediator, is associated with MS-related fatigue. This is in support of a pathogenic role of the MS-related inflammatory process in the development of fatigue.

References

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