Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression

The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the α2δ Subunit of a Calcium Channel

N S Gee, Jason P. Brown, Visaka U.K. Dissanayake et al. · Journal of Biological Chemistry · 1996 · 1.2K citations · Full text

Medicine, Neuroscience, Pharmacology +15

Upregulation of Dorsal Root Ganglion α₂δ Calcium Channel Subunit and Its Correlation with Allodynia in Spinal Nerve-Injured Rats

Z. David Luo, Sandra R. Chaplan, Emiliano S. Higuera et al. · Journal of Neuroscience · 2001 · 613 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Calcium channel currents and their inhibition by (‐)‐baclofen in rat sensory neurones: modulation by guanine nucleotides.

Annette Dolphin, Roderick H. Scott · The Journal of Physiology · 1987 · 341 citations

Life Sciences, Neuroscience, Pharmacology +17

Calcium Channel α₂δ Subunits—Structure and Gabapentin Binding

Elsé Marais, Norbert Klugbauer, Franz Hofmann · Molecular Pharmacology · 2001 · 262 citations

Life Sciences, Neuroscience, Pharmacology +17

Gabapentin inhibits high‐threshold calcium channel currents in cultured rat dorsal root ganglion neurones

Kathy Sutton, Duncan J. Martin, R.D. Pinnock et al. · British Journal of Pharmacology · 2002 · 240 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17