Frontiers in Plant Science · 2011 · 463 citations · 53 references
Life SciencesPlant BiologyPlant SciencesComputational BiologyPlant Cell BiologyPlant Molecular BiologyBiocontrol Of Plant DiseasesCyber-physical Systems ArchitectureCollaborative Research InfrastructureCross-disciplinary Knowledge IntegrationHigh-performance Computing Systems
Meeting growing demands for agricultural and forest products and sustainable ecosystem management requires synergies from information technologies. The iPlant Collaborative is an NSF‑funded initiative to develop an innovative, comprehensive cyberinfrastructure that enables plant biologists to tackle grand challenges, foster cross‑disciplinary research, and train future scientists. iPlant’s design, built on extensive community input, leverages high‑performance computing, data storage, and open‑source APIs, and is supported by workshops that teach researchers how to integrate bioinformatics tools and datasets for large‑scale analyses without command‑line expertise. Workshops have enabled researchers to integrate bioinformatics tools and datasets into iPlant, allowing complex large‑dataset analyses without command‑line or HPC expertise.
The iPlant Collaborative (iPlant) is a United States National Science Foundation (NSF) funded project that aims to create an innovative, comprehensive, and foundational cyberinfrastructure in support of plant biology research (PSCIC, 2006). iPlant is developing cyberinfrastructure that uniquely enables scientists throughout the diverse fields that comprise plant biology to address Grand Challenges in new ways, to stimulate and facilitate cross-disciplinary research, to promote biology and computer science research interactions, and to train the next generation of scientists on the use of cyberinfrastructure in research and education. Meeting humanity's projected demands for agricultural and forest products and the expectation that natural ecosystems be managed sustainably will require synergies from the application of information technologies. The iPlant cyberinfrastructure design is based on an unprecedented period of research community input, and leverages developments in high-performance computing, data storage, and cyberinfrastructure for the physical sciences. iPlant is an open-source project with application programming interfaces that allow the community to extend the infrastructure to meet its needs. iPlant is sponsoring community-driven workshops addressing specific scientific questions via analysis tool integration and hypothesis testing. These workshops teach researchers how to add bioinformatics tools and/or datasets into the iPlant cyberinfrastructure enabling plant scientists to perform complex analyses on large datasets without the need to master the command-line or high-performance computational services.
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The Sequence Alignment/Map format and SAMtools
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Biological identifications through DNA barcodes
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