Malignant lymphoma in African children.II. A pathological entity

Abstract

N THE PREVIOUS communication the clinical I aspects of 106 cases of malignant lymphoma were discussed, and the principal sites of tumor manifestations were described so as to emphasize the existence of a readily recognizable syndrome in African children.2 Although the pathological anatomy and the organ distribution of this syndrome are not significantly dissimilar in many respects to malignant lymphoma as known elsewhere, certain unique features of the disease, and indeed the sheer force of numbers, prompt a more detailed discussion of these aspects, some histological description and classification, and a few comments as to probable histogenesis. T h e remarks as to organ distribution are based on obvious clinical manifestations in all of the 106 cases, the recorded findings at 13 laparotomies, and on 28 postmortem examinations. T h e histological description, of course, is the result of study of the biopsy and autopsy material from all the cases reported in the first paper.