Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection

Lorraine M. Albritton, Lena Tseng, David T. Scadden et al. · Cell · 1989 · 695 citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease

John Collinge, Mark S. Palmer, Aidan J. Dryden · The Lancet · 1991 · 566 citations

Life Sciences, Genetics, Molecular Genetics +12

Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie

Peter B.G.M. Belt, I. H. Muileman, B. E. C. Schreuder et al. · Journal of General Virology · 1995 · 442 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

PrP Genotype and Agent Effects in Scrapie: Change In Allelic Interaction With Different Isolates of Agent in Sheep, a Natural Host of Scrapie

Wilfred Goldmann, Nora Hunter, George Davey Smith et al. · Journal of General Virology · 1994 · 438 citations

Veterinary Medicine, Infectious Diseases, Pathobiology +14

Two alleles of a neural protein gene linked to scrapie in sheep.

Wilfred Goldmann, Nora Hunter, James D. Foster et al. · Proceedings of the National Academy of Sciences · 1990 · 302 citations · Full text

Veterinary Medicine, Genetics, Molecular Genetics +15