Antimicrobial Agents and Chemotherapy · 2008 · 65 citations · 10 references
Life SciencesGeneticsMicrobiologyAntimicrobial ResistanceBacteriologyMicrobial GeneticsAntibiotic ResistanceAntibiotic Resistance GeneticsAntibiotic Resistance MechanismsAntimicrobial Resistance GenomicsMechanisms Of Antimicrobial ResistanceResistance GenesAntibiotic Resistance GenesAntimicrobial Resistance Gene DetectionChromosomally Encoded Resistance DeterminantsEscherichia ColiFluoroquinolone Resistance MechanismsQuinolone Resistance GenesQuinolone Resistance MechanismsResistance In Clinical Isolates
A new chromosome-carried quinolone resistance gene from Stenotrophomonas maltophilia, Smqnr, was characterized. The gene was present in type strain CCUG 5866 and was also detected in 24 clinical isolates and showed some allelic diversity. The expression of Smqnr in Escherichia coli decreased the susceptibilities of the E. coli isolates to several fluoroquinolones.
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George A. Jacoby, Vincent Cattoir, David C. Hooper et al. · Antimicrobial Agents and Chemotherapy · 2008 · 201 citations · Full text