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DBU‐catalyzed three‐component one‐pot synthesis of highly functionalized pyridines in aqueous ethanol
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References
2009
Year
Chemical EngineeringEngineeringHeterocyclicExcellent YieldNatural SciencesDiversity-oriented SynthesisAqueous EthanolJ. Heterocyclic Chem.Organic ChemistryCatalysisChemistryImage 1,8‐DiazabicycloHeterocycle ChemistrySynthesis MethodThree‐component One‐pot SynthesisSynthetic ChemistryEnantioselective SynthesisCatalytic Synthesis
Abstract magnified image 1,8‐Diazabicyclo[5.4.0]undec‐7‐ene (DBU) efficiently catalyzes three‐component one‐pot condensations of aldehyde, malononitrile, and thiophenol to produce highly functionalized pyridines in excellent yield in aqueous ethanol. J. Heterocyclic Chem., 46 , 69 (2009).
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