Resveratrol Induced Serine Phosphorylation Of p53 Causes Apoptosis In A Mutant p53 Prostate Cancer Cell Line

Abstract

Resveratrol causes apoptosis in DU 145 prostate cancer cells. This action depends on the activation of MAPK, increase in cellular p53 content, serine-15 phosphorylation of p53 and increased p53 binding to DNA.