Fluorogenic detection of hydrogen sulfide via reductive unmasking of o-azidomethylbenzoyl-coumarin conjugate

Abstract

Selective detection of hydrogen sulfide was achieved with 7-o-2'-(azidomethyl)benzoyl-4-methylcoumarin via analyte mediated reductive removal of the 2'-(azidomethyl)benzoyl moiety and concurrent generation of fluorescent 7-hydroxy-4-methylcoumarin.