Neurology · 1991 · 50 citations · 0 references
Life SciencesGeneticsMolecular GeneticsHuman GeneticsMedical GeneticsPediatric GeneticsChromosomal DisordersGenetic DisordersMendelian DisordersNeurogenetic DisordersStructural Chromosome AbnormalitiesTourette SyndromeAttention-deficit DisorderAutosomal Dominant InheritanceDisorderGilles De La Tourette SyndromeInherited Chromosomal DisordersObsessive-compulsive Disorder GeneticsTic Disorder Genetics
Gilles de la Tourette's syndrome (GTS) is a genetic disorder characterized by multiple motor and vocal tics, obsessive-compulsive disorder, and attention-deficit disorder. Family studies support the presence of an autosomal dominant gene; however, to date, an assignment for the GTS locus has not been made. We present the case of a boy with GTS and a deletion of the terminal portion of the short arm of chromosome 9, del(9)(qter----p2304:).