Efficacy of Omeprazole for the Treatment of Symptomatic Acid Reflux Disease Without Esophagitis

Abstract

Patients with symptomatic GERD require profound acid suppression to achieve symptomatic relief. Omeprazole, 20 mg once daily, was superior to omeprazole, 10 mg once daily, and to placebo in providing early and sustained resolution of heartburn, as well as treatment of other troublesome GERD symptoms.