Organic Letters · 2014 · 27 citations · 28 references
Natural SciencesChemistryCatalysisOrganic ChemistryCatalyst DesignCatalyst SynthesisCatalytic MechanismsHeterocycle SynthesisOrganic SynthesisAlkylation CatalysisAlkylation ReactionsAryl Halide CouplingNucleophile ReactivityPalladium CatalystsPalladium-catalyzed Cross-coupling
The alkylation of (Z)-3-aryl-2-fluoroallyl acetate with the malonate anion by the [Pd(C3H5)(cod)]BF4/2,2'-bpy catalyst proceeds through the carbon-fluorine bond cleavage, and 2 equiv of the malonate nucleophile was introduced to the allyl substrate.
28