Chronometric Infusor — An Apparatus for Protracted Ambulatory Infusion Therapy

Abstract

IT is desirable to prolong current forms of regional cancer infusion therapy by the use of a mechanism permitting, on an ambulatory, outpatient basis, parenteral administration of fluid containing antimetabolite drugs. A device has been developed and is currently in use on the cancer chemotherapy service at the Lahey Clinic to infuse small volumes of drug (3 to 5 ml. in twenty-four hours) accurately for periods of weeks or even months. The mechanism is also proving valuable in the animal laboratory since it permits the continuous parenteral infusion of drugs into unrestrained large animals (dogs).The miniaturized self-contained infusion assembly . . .