Inhibition of intragastric acidity in healthy subjects dosed with ranitidine 75 mg: a comparative study with cimetidine and placebo - Concepedia

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Inhibition of intragastric acidity in healthy subjects dosed with ranitidine 75 mg: a comparative study with cimetidine and placebo

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References

1997

Year

C. E. GRIMLEY, S Constantinides, C.C.L. Snell, J. G. MILLS, Chuka Nwokolo

Alimentary Pharmacology & Therapeutics

Abstract

In healthy subjects, the inhibitory effect of ranitidine 75 mg on intragastric acidity can be detected 10-15 h after an oral dose. By contrast, the inhibitory effect of cimetidine 200 mg seems to be restricted to the first 10 h.