Asymmetric Synthesis of the Polyol Portion of the Polyene Macrolide Antibiotic RK-397 - Concepedia

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Asymmetric Synthesis of the Polyol Portion of the Polyene Macrolide Antibiotic RK-397

DOI Full Paper Access

20

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0

References

2002

Year

Christoph Schneider, Frank Tolksdorf, Markus Rehfeuter

Synthetic MacromoleculeEngineeringPolymer ScienceAsymmetric SynthesisNovel Polyol SynthesisOrganic ChemistryChemistryBiomolecular EngineeringPolyol PortionPolymer ReactionSynthetic ChemistryPolymer ChemistryPolymer Synthesis

Abstract

A highly convergent and asymmetric synthesis of a fully functionalized polyol portion of the new polyene macrolide antibiotic RK-397 has been achieved taking advantage of a novel polyol synthesis.