Pharmacophore mapping of a series of pyrrolopyrimidines, indolopyrimidines and their congeners as multidrug-resistance-associated protein (MRP1) modulators

PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results

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Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 bound to Mg2+/ATP Reveals a Non-productive Catalytic Site

Odile Ramaen, Nicolas Leulliot, Christina Sizun et al. · Journal of Molecular Biology · 2006 · 87 citations

Life Sciences, Biochemistry, Molecular Biology +15

Studies on Pyrrolopyrimidines as Selective Inhibitors of Multidrug-Resistance- Associated Protein in Multidrug Resistance

Shouming Wang, Adrian Folkes, Irina Chuckowree et al. · Journal of Medicinal Chemistry · 2004 · 79 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

2,4,5-Trisubstituted imidazoles

Chengzhi Zhang, Sepehr Sarshar, Edmund J. Moran et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 62 citations

Structure–activity relationships of a series of tariquidar analogs as multidrug resistance modulators

Christoph Globisch, Ilza Pajeva, Michael Wiese · Bioorganic & Medicinal Chemistry · 2005 · 48 citations

Medicine, Medicinal Chemistry, Pharmacology +12