A PHASE I/II TRIAL OF TRANSURETHRAL SURGERY COMBINED WITH CONCURRENT CISPLATIN, 5-FLUOROURACIL AND TWICE DAILY RADIATION FOLLOWED BY SELECTIVE BLADDER PRESERVATION IN OPERABLE PATIENTS WITH MUSCLE INVADING BLADDER CANCER

Abstract

This pilot study demonstrates a high rate of response to this combined chemotherapy/radiation regimen in conjunction with a visibly complete transurethral resection. Reevaluation after a short induction phase allows for the early selection of patients with persistent disease for radical cystectomy.