Annals of Internal Medicine · 1970 · 139 citations · 10 references
Life SciencesInfectious DiseasesMicrobiologyBacteriologyMedical MicrobiologyPulmonologyClinical BacteriologyPulmonary InfectionsRespiratory DiseaseRespiratory InfectionsRespiratory Infectious DiseasesRespiratory Tract InfectionsPneumonia DiagnosisRespiratory Bacterial DiagnosticsSputum ExaminationSputum MicrobiologySputum Specimen Collection
Transtracheal aspiration was compared with routine expectorated sputum for bacteriologic results in 61 patients with acute pneumonia and no recent antimicrobial therapy. The procedure was safe, produced a high yield of pulmonary pathogens, and provided a sample of lower respiratory tract secretions relatively free of contamination by mouth flora. Gram stains of tracheal specimens correlated better with their corresponding cultures than did the smears of expectorated sputum. Transtracheal aspiration was most helpful in obtunded patients unable to raise sputum and in patients whose expectorated sputum contained large numbers of staphylococci or gram-negative bacilli. Quantitative sputum cultures also were performed on 24 patients but did not accurately predict the organisms likely to be recovered by transtracheal aspiration.
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Diagnostic Usefulness and Safety of Transtracheal Aspiration
Robert W. Kalinske, Richard H. Parker, D. Brandt et al. · New England Journal of Medicine · 1967 · 177 citations
PNEUMONIAS CAUSED BY GRAM NEGATIVE BACILLI
James R. Tillotson, A. Martin Lerner · Medicine · 1966 · 160 citations
AN EVALUATION OF SPUTUM EXAMINATION IN CHRONIC BRONCHITIS
W. Brumfitt · The Lancet · 1957 · 126 citations