Enantioselective Catalytic Hydrogenation

Abstract

Very different ligands have been employed recently for enantioselective hydrogenation. With rhodium phospholane complexes, not only the usual, but also highly substituted enamides such as 1 and acylhydrazones can be hydrogenated. With ruthenium complexes containing chiral amino alcohols, ketones can be converted into the corresponding alcohols with high enantioselectivities.